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Publications:

 

Heider S., Reimhult, E., Metzner, C. (2018) Real-time analysis of protein and protein mixture interaction with lipid bilayers. Biochimica et Biophysica Acta (BBA) – Biomembranes. Volume 1860, Issue 2, February 2018, Pages 319-328

 

Heider S, Muzard J, Zaruba M, Metzner C. (2017) Integrated Method for Purification and Single-Particle Characterization of Lentiviral Vector Systems by Size Exclusion Chromatography and Tunable Resistive Pulse Sensing. Mol Biotechnol. Jul;59(7):251-259.

 

Heider S., Dangerfield, J.A., Metzner, C. (2016) Biomedical applications of glycosylphosphatidylinositol-anchored proteins. Journal of Lipid Research Oct; 57(10):1778-1788. doi: 10.1194/jlr.R070201.

 

 

Heider, S., Kleinberger, S., Kochan, F., Dangerfield, J.A., Metzner, C. (2016) Immune Protection of Retroviral Vectors Upon Molecular Painting with the Complement Regulatory Protein CD59. Molecular Biotechnology, May 11. Download

 

 

[Comment on Patel et al.] Metzner, C., Salmons, B., Gunzburg W.H., Dangerfield, J.A. (2015) "Protein transfer-mediated surface engineering to adjuvantate virus-like nanoparticles for enhanced anti-viral immune responses" Nanomedicine, 11(5): p. 1097-107. PubMed Link

 

 

[Published thesis] Spurny, B., (2014) Optimization of Delivery of Functional GPI-IL2 to Virus-like Particles Using Molecular Painting. Inst. of Virology. University of Veterinary Medicine, Vienna, p. 50.

 

 

[Published thesis] Schöchtner, S., (2014) Molecular Painting of HIV-1 Virus-like Particles with Interleukin-2 for Immune Stimulation. Inst. of Virology. University of Veterinary Medicine, Vienna, p. 112.

 

 

[Important publication from other group] Colhone, M.C., Silva-Jardin, I., Stabeli, R.G., and P. Ciancaglini. (2014) Nanobiotechnologic approach to a promising vaccine prototype for immunisation against leishmaniasis: a fast and effective method to incorporate GPI-anchored proteins of Leishmania amazonensis into liposomes. Journal of Microencapsulation. DOI: 10.3109/02652048.2014.958203. Sep 29: 1-8. Download

 

 

Heider, S. and Metzner, C. (2014) Quantitative real-time single particle analysis of virions. Virology (462-463), p199-206. Download

 

 

Heider, S., Kochan, F., Kleinberger, S., Sperl, E., Reimhult, E., Metzner, C., (2013) Investigating retroviral envelope proteome plasticity. Retrovirology 10, S26-S26.

 

 

Metzner, C., Kochan, F. and J.A. Dangerfield. (2013) Post-exit surface Engineering of Retroviral/Lentiviral Vectors. BioMed Research International, Mar 15, Volume 2013, Article ID 253521, 8 pages. http://dx.doi.org/10.1155/2013/253521 Download

 

 

Metzner, C., Kochan, F. and J.A. Dangerfield. (2012) Fluorescence Molecular Painting of enveloped viruses. Molecular Biotechnology, Oct 28, 

DOI: 10.1007/s12033-012-9616-6. Download

 

 

Kochan, F., Dangerfield, J.A., Gunzburg, W.H., Salmons, B., Metzner, C., (2012) A modular system for transduction targeting of viral vectors for gene therapy. Human Gene Therapy 23, A126-A126.

 

 

Metzner, C., Kochan, F., Gunzburg, W.H., Salmons, B., Dangerfield, J.A., (2011) Post-exit viral surface engineering: An update on molecular painting. Human Gene Therapy 22, A104-A104. PubMed Link

 

 

Metzner, C., Salmons, B., Günzburg, W.H. and J.A. Dangerfield. (2008) Rafts, anchors and viruses – A role for glycosylphosphatidylinositol-anchored proteins in the

modification of viruses and viral vectors. Virology 382(2): 125-31. Download

 

 

Lear, M.J., Salmons, B., Gunzburg, W.H. and J.A. Dangerfield. (2009) Singapore R&D and globetrotting. Biotechnology Journal, 4, 179-185. DOI 10.1002/biot.200800131. Download

 

 

Metzner, C., Mostegl, M.M., Günzburg, W.H., Salmons, B. and J.A. Dangerfield. (2008) Association of glycosylphosphatidylinositol-anchored protein with retroviral particles. FASEB Journal 22(8): 2734-2739. Download

 

 

 

Books and Book Chapters:

 

 

Metzner, C. and Dangerfield, J.A. (2011) Chapter 3: “Surface modification of retroviral vectors for gene therapy” p. 41-72, in K. Xu (ed.), “Viral Gene Therapy”, vol. 1. InTech Open Access Publishers. E-Book, eISBN: 978-953-307-539-6. Read full article online free

 

 

E-Book: “GPI Membrane Anchors  - The Much Needed link”. Bentham Science Publishers. J. Dangerfield (ed.), C. Metzner (co-ed.). eISBN: 978-1-60805-123-6, June 2010. Purchase online

 

 

Metzner, C., Legler, D.F. and Dangerfield, J.A. (2010) Chapter 6: “Surface engineering of biomembranes with GPI-anchored proteins and its applications”, p. 83-97 in J. A. Dangerfield, Metzner C. (ed.), “GPI Membrane Anchors - The Much Needed Link”, vol. 1. Bentham Science Publishers. E-Book, eISBN: 978-1-60805-123-6. Download

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Press:

 

Article: "Molecular painting sparks biologics research", Singapore, BioSpectrum, August 2012. View original article online, or download

     

 

Article: “Painting at the Molecular Level", Singapore, BioNet Asia Pacific, July 2012, pages 39-42. Download

 

 

Article: “Simply paint viruses: new biotech method to track viruses in the body”, Austria, Universum Magazine, August 2010, page 77. [article in German] Download

 

 

Release: “Researchers create virus-based technique to study disease”, Singapore, The Straits Times, Saturday June 14, 2008, page H6.

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Membrane anchors